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Genetically engineered bacteria as inflammatory bowel disease therapeutics

Selectable Marker Genes Examples of suitable markers include, the dihydrofolate reductase gene (DHFR), the thymidine kinase gene (TK), or prokaryotic genes conferring drug resistance, gpt (xanthine- guanine phosphoribosyltransferase, which can be selected for with mycophenolic acid

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However, only post-treatment plasma acetylglycine showed a statistically significant increase from 2.42 0.97 to 3.06 1.50 mol/L (p = 0.002) (Supplementary Table 3)