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Cellular Signaling Pathway Integration GHK-Cu activates or modulates multiple cellular signaling cascades that integrate regenerative responses across tissue systems

10.1016/s0140-6736(87)91988-x [DOI] [PubMed] [Google Scholar] 189.Iliev ID, Leonardi I

Ailanthone, a novel inhibitor targeting transcription factor c-Jun, downregulates PD-L1 expression in melanoma cells while reducing infiltration of immunosuppressive regulatory T cells (Tregs) in tumors, thereby potentiating anti-PD-L1 antibody therapy (35)

[DOI] [PMC free article] [PubMed] [Google Scholar] 89.Waetzig V., Czeloth K., Hidding U., Mielke K., Kanzow M., Brecht S., et al

GO enrichment analysis and GSEA showed that ATF4 was closely related to autophagy and the mTORC1 pathway, respectively ( Figure 8 )

21 Belman was the pioneer to reveal chemopreventive effects of garlic oil against skin tumorigenesis initiated by DMBA and promoted by PMA