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The panel of AdA and Asp performed well in identifying DILI patients with a high risk of chronicity at the early stage of the disease, which could help with early intervention in clinical practice

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In certain pathological conditions (such as periodontitis), high levels of methyl mercaptan (MeSH) act as a competitive false substrate for SQOR, reacting with the enzyme to form persulfide products (MeSSH) that cannot be further metabolized

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