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Although maintaining adequate vitamin B12 levels in the body is essential for normal cellular functions, however, sufficient research-based evidence is not yet available to claim the importance of vitamin B12 in cancer prevention

The absorption process is significantly hindered in conditions such as pernicious anemia, Crohns disease, celiac disease, and following ileal surgical resection, all of which can impair B12 absorption and contribute to suboptimal supplementation outcomes

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[8] Similarly, patients with gout or hyperuricemia should avoid high niacin intake, as niacin (even in nicotinamide form) can raise uric acid levels and potentially trigger gout flares

For documented deficiency, loading doses of 1000 mcg daily or several times weekly for 1 to 2 weeks rapidly restore tissue levels

HCG also triggers the female body to produce more estrogen