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Functional NMDA receptors in rat erythrocytes

It supports phase II liver detoxification by conjugating and eliminating certain undesirable compounds

Translating these in vitro findings to an in vivo model, naturally aged male mice from 20-24 months old were treated with FOXO4-DRI

The AuNPs were characterized by UVVis spectroscopy and TEM

Atpenin A5 is, up to now, an experimental compound that was not tested in vivo, possibly due to its expectable multiple adverse effects in various organs

Furthermore, activation of intestinal liver X receptor alpha (LXR) by dietary cholesterol has been implicated in accelerating hepatic carcinogenesis, highlighting the role of diet-driven signaling in the initiation of HCC [80]