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Taking more vitamin B12 will not harm you because it is excreted through the kidneys, but you should not take too much vitamin B12

A deficiency can erode this coating and cause neuropathy (tingling, numbness, or pain in the hands and feet)

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One naturally occurring peptide, Epithalamin, produced in the pineal gland, has been linked to increased melatonin production, enhanced immune and anti-carcinogenic functions in rodent models, and restoration of reproductive function in aged rodents

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Insulin, oxytocin, GLP-1, these aren't pharmaceutical inventions, they're native signals your biology already knows how to read