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The importance of serine metabolism in cancer

This combinatorial strategy may not only enhance anti-tumor immune responses through the release of DAMPs and tumor-associated antigens from ferroptotic cells but also simultaneously induce selective and potent cell death in GBM, potentially overcoming therapeutic resistance mechanisms

(PubMed) Press M, Hartop PJ, Prottey C

Deletion of ABCB1 in UO-31 cells increases sensitivity to erastin derivatives The renal carcinoma cell line UO-31 is known to have detectable levels of P-gp and displays rhodamine efflux [21]

However, because long-term human data is limited, ongoing monitoring of IGF-1 levels, glucose, and overall health is strongly recommended

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