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Cochrane Database Syst Rev 2010(7) Sugiura H, Yoshida T, Tsuchiya K, Mitobe M, Nishimura S, Shirota S, Akiba T, Nihei H (2005) Klotho reduces apoptosis in experimental ischaemic acute renal failure

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These results suggest that sst2 activation might account for the tonic inhibition induced by SST, while simultaneous sst1 recruitment would promote the irregular, rebound-like, pattern

Approximately 2 million deaths annually are attributed to liver diseases, representing 4% of global mortality