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172,173,174 This represents a major advance as the first successful PROTAC-mediated degradation of an ER-localized, polytopic transmembrane protein, opening new possibilities for metabolic intervention

These results suggest that the anti-RGMa antibody specifically improves the development and the survival of DCX-positive immature neurons in the context of insulin-resistant type 2 diabetes, without altering NSC proliferation

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Under oxidative stress, autophagy protects mitochondrial integrity by clearing ROS, preventing cell apoptosis, and exerting a protective effect (95)

CIT and DH-CIT in urine represent, on average, 40% of the CIT uptake, based on a study involving two individuals

Some of the most challenging infrastructure projects require bridges and boardwalks to traverse steep hillsides, deep ravines, dramatic elevation changes, wetlands, mountain slopes, coastal bluffs, and environmentally sensitive landscapes