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Moreover, while the drafting of this paper was underway, a 10-week, randomized, placebo-controlled, double-blind trial to evaluate the effect of NMN supplementation on metabolic function in 25 postmenopausal women with prediabetes was reported 21 , in which NMN supplementation increased muscle insulin sensitivity, insulin signaling, and remodeling in women with prediabetes who are overweight or obese 21

Nature,2000, 408 (6809): 23947 34

& Dziadek, J

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Most doctors, how much peer reviewed literature do you think most doctors who are in orthopedic surgeons who are in practice, how much are they absorbing