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doi: 10.3389/fimmu.2018.01961 150 WangQWuH

Hence, ROP is a useful synthetic pathway to induce disulfide crosslinking in nanogel-based DDSs

G values were computed by comparing the energy of the wild-type protein to that of the mutant in its most stable conformation

The incidence of severe gastrointestinal adverse events leading to treatment discontinuation was higher with tirzepatide compared to some comparators but remained within acceptable ranges for most patients