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In addition, daratumumab has been conjugated to DOTA for radiolabeling with the alpha-emitter actinium-225 ( 225 Ac), showing potent CD38-positive tumor cell-killing in vitro and enhanced anti-tumor activity (~ 30-fold) in vivo without significant side effects [131]

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Always consult with your healthcare provider before starting weight loss therapy with tirzepatide to ensure safety and effectiveness

[DOI] [PMC free article] [PubMed] [Google Scholar] 66.Grant, R