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Description

The elimination of orforglipron occurs predominantly through hepatic metabolism, with Phase I oxidative biotransformation as the principal clearance mechanism

Funding This study was supported by the State Key Laboratory of Trauma, Burn and Combined Injury (SKLYQ202002 to YC), Southwest Hospital (SWH2018BJKJ-05 to YC), National Natural Science Foundation of China (82030036 to HF), and Chongqing Talent Program (4139Z2391 to HF)