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Maps sharpened less aggressively ( B -factor of 15.0 2 ) confirmed unambiguously that this feature was due to the presence of CP17 bound at the interprotomer pocket of the wt PV2 VLP (Fig

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A more sensitive method of screening for vitamin B 12 deficiency is measurement of serum methylmalonic acid and homocysteine levels, which are increased early in vitamin B 12 deficiency

doi: 10.1038/s12276-022-00736-w 89 YamazakiTHannaniDPoirier-ColameVLadoireSLocherCSistiguAet al