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Sulforaphane and its bifunctional analogs: synthesis and biological activity

Int J Neuropsychopharmacol 18

Additionally, studies have shown that fatty acids produced by gut microbes, especially unsaturated fatty acids, are closely associated with the inflammatory state of IBD [12, 13]

This is turn leads to skin inflammation and irritation like white heads, redness, and heat

& Bryce, P

Broadly, interventions fall into a few categories: dietary modifications and prebiotics, probiotic supplementation, fecal microbiota transplantation, direct microbial metabolite (postbiotic) supplementation, and emerging approaches like phage or small-molecule therapies targeting microbial pathways