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H 2 S activates Nrf2 by S-sulfhydrating Kelch-like ECH-associated protein 1 (Keap1), which releases Nrf2 from repression, thereby mitigating oxidative stress (Hourihan et al., 2013)

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This finding established that dysregulated activation of IKK/NF-B signaling in chondrocytes is a key driver in the onset of age-related osteoarthritis

Reduced mucociliary clearance in old mice is associated with a decrease in Muc5b mucin

Howlett M, Giraud AS, Lescesen H, Jackson CB, Kalantzis A, Van Driel IR, et al

Using this cutoff, the prevalence of vitamin E inadequacy among US adults (20 years, excluding pregnant and lactating women) is extremely low ( 31 mmol/L vs