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(2022) 14(2):e22371

10.1177/039463200401700103 142 SunY.JiaZ.LiuG.ZhouL.LiuM.YangB.et al (2013)

While steroids are highly effective at building lean muscle mass rapidly , they can also cause side effects such as: Gynecomastia Hair loss or acne Increased risk of heart disease or stroke Suppression of natural testosterone production Liver and kidney toxicity in oral compounds (Pope et al., 2014, Endocrine Reviews ) Legal and Regulatory Status The legal classification of peptides and steroids varies widely by country and region : Peptides : Many are approved for medical use (e.g., for growth hormone deficiency, wound healing), and some can be obtained via prescription

Additionally, it causes both microgliosis and astrogliosis, which is characterized by increased astrocytic proliferation in rat cortex and striatum accompanied by a marked expression of GFAP [92,93]