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In addition, it has been observed that stimulating NLRP3 inflammasome assembly can induce depression-like behaviors in rodents exposed to LPS or CUMS

To quantitatively assess the relationship of BRD4 and MLL4 binding partners, we measured binding affinities of BRD4 ET and MLL4 PHD2/3 to the region of ASXL1 containing both ASXL1 EBM and ASXL1 MBH (aa 564-635 of ASXL1, ASXL1 EBM-MBH ) (Fig

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Therefore, receptor-mediated transcytosis allows the specific targeting of larger drug molecules or drug-carrying particles (such as liposomes, polymer systems, nanoparticles) to the brain

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doi: 10.1016/j.chom.2018.01.006 102 BondetVLe BautMLe PoderSLcuAPetitTWedlarskiRet al