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These findings validated our initial selection, leading us to focus on the further characterization of the KIN-19/NHR-49 phosphorylation event

doi: 10.1016/j.tplants.2012.04.005 78 KepplerL

Similarly, OGDH and BCKDH catalyze oxidative decarboxylations of -ketoglutarate (to succinyl-CoA) and branched-chain -keto acids (from valine, leucine, and isoleucine), involving: CO 2 release

doi: 10.1016/0006-3002(57)90141-5 84 ChanceBBaltscheffskyH

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In sum, a host of pharmacologic agents from novel small molecules to repurposed anesthetic drugs are being utilized to stabilize mitochondria, reduce DAMPs release, and optimize immune cell metabolism during the perioperative period