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doi: 10.1159/000380771 107 ChalmersJDGoeminnePAlibertiSMcDonnellMJLonniSDavidsonJet al

Insights from these assays mitigate the risk of late-stage conflicting data, drug candidates being wrongly abandoned as toxic or mistakenly classified as safe

Biochim Biophys Acta 1269: 153161, 1995 [DOI] [PubMed] [Google Scholar] 44

75 These techniques, however, could not detect DNA interstrand cross-linking in mammalian cells exposed to therapeutic levels of alkylating agents in vitro or in tissues after in vivo drug administration

Benzene and its phenolic metabolites produce oxidative DNA damage in HL60 cells in vitro and in the bone marrow in vivo Cancer Res 1993 53 : 10231026 Lvay G, Bodell WJ

It strengthens white blood cells, supports cell production, and helps regulate inflammationall key factors in fighting illness and maintaining resilience