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Most of the anti-inflammatory effects of PPARs result from their inhibition of the NF-B signaling pathway, which also inhibits the production of various genes implicated in the inflammatory response, including iNOS, IL-6, and IL-12 58

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Lancet 2009;374:1252-61.ArticlePubMed 85

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Glutarate regulates T cell metabolism and anti-tumour immunity

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The kisspeptinGnRH pathway provides additional mechanistic insight

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The mixture was neutralized by the addition of 1 L of 5 M HCl solution and then purified using 52 L of RNAcleanXP

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