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Glutathione is required to regulate the formation of native disulfide bonds within proteins entering the secretory pathway*

Nutrients 10 , 1203 (2018)

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Both of them hydrolyse the ester bonds to produce alcohols and acids as metabolites via a two-step reaction which involves nucleophilic attack of the serine residue on the carbonyl carbon of the ester bond, followed by a second nucleophilic attack by water molecules to replace the acyl group, resulting in the release of the free active enzyme and acidic moiety of the carboxylic ester [114, 115]

In contrast, type II NKT cells are activated by sulfonamide compounds and can inhibit the activity of type I NKT cells [110]