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The roles and applications of short-chain fatty acids derived from microbial fermentation of dietary fibers in human cancer

2013;127(1):e6e245

some researchers speculate that 7-HMR, like other plant lignans, can act as a phytoestrogen and thereby modulate inflammatory pathways linked to hormonal signaling (63)

In hepatocellular carcinoma, glutathione S-transferase Pi (GSTP) translocates to the nucleus and modulates redox signaling via the Nrf2-Keap1 complex

The strength of evidence for critical and essential outcomes was rated based on study design, risk of bias, consistency, limitations, directness, reporting precision and publication bias (Balshem et al

KEGG pathway analysis showed that downregulated acetylated proteins were involved in the pathway of fatty acid metabolism, oxidative phosphorylation, TCA cycle, metabolic pathways, and necroptosis (Figure 3E, Supplementary Material 6)