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It may reduce compounds in the immediate environment of the cell and might protect cells [23]

The cells were incubated in 6-well plates (2 mL/well) at a density of 150,000 per well for 24 h, followed by treatment with test compounds with or without cisplatin (1 M) for 48 h

however, some drugs can cause chronic damage and may even lead to tumor growth (Table 1)

Furthermore, the beneficial effect of glutathione on H 2 O 2 -induced DNA damage was significantly reduced by ZnPP, which also implies that the protective role of glutathione on H 2 O 2 -induced cytotoxicity was dependent on HO-1

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This process is known as the Gamma-glutamyl cycle