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Excitotoxicity also ensues, whereby excess extracellular glutamate overactivates NMDA receptors, increasing intracellular calcium levels and triggering protease activation and nitric oxide production ( Furthermore, oxidative stress arises from mitochondrial dysfunction and inflammation (Khan et al., 2022)

Contrary to the classic Warburg effect observed in some cancers, the upregulation of glycolysis in SLE T cells is not accompanied by a suppression of mitochondrial metabolism (76, 83)

Proc Natl Acad Sci U S A 103:1308691, PMID: 16916935 Rao RK, Clayton LW (2002) Regulation of protein phosphatase 2A by hydrogen peroxide and glutathionylation

2009), (2) conjugation of GSH to electrophiles (Ehrke et al

Since liposomes have a similar phospholipid composition to the lipid membranes of human cells, they are significantly better absorbed into the bodys cells