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An important philosophical perspective on the value of simplicity, in contrast to the frequent academic tendency to promote expensive and intricate solutions

Albersen, M

Carotid stenosis (narrowing of the carotid arteries, which are the main vessels that supply blood to the brain)

Trends in Endocrinology and Metabolism

Rotate sites: Rotate injection sites systematically ( abdomen, thighs, upper arms ) to reduce irritation, redness, and tissue buildup

Combine this with a genetic variant for an enzyme called diamine oxidase (DAO), the main enzyme responsible for metabolizing ingested histamine, and the result is high histamine which can lead to headaches