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Intracellular ROS levels were quantified using an H2DCFDA kit (MedChemExpress, USA)

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25 In a controlled trial in 41 patients with sudden sensorineural hearing loss, those who received NAC along with intratympanic (through the eardrum) injections of the steroid dexamethasone for 14 days gained an ability to hear a specific high pitch (8,000 Hz) and were more likely to recover their hearing than those who received intratympanic steroid injections alone

(Source 3) Curcumin Curcumin is the active anti-inflammatory and antioxidant constituent of turmeric

Lastly, when comparing children with stage 3 konzo with their unaffected siblings, we found that in addition to GPx3, Zinc-alpha-2-glycoprotein (AZGP1) and Carboxypeptidase B2 (CPB2) were major contributors to group segregation, with CP protein also being identified as being a potential contributor (Fig

If peptide budget is a significant constraint