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Several of these miRNAs target mRNAs encoding AR, AR splice variants or components of the AR protein interactome [109, 110]

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4.1 Betaine in hyperhomocysteinemia The elevated plasma total homocysteine (i.e., hyperhomocysteinemia) is a known risk factor for CVDs (Refsum et al., 1998) and is also associated with some neurological disorders ( 4.2 Betaine in cardiovascular diseases Hyperhomocysteinemia is a risk factor for CVDs (Refsum et al., 1998)