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Description

Patients with early Lebers disease (hereditary optic nerve atrophy) who were treated with vitamin B12 suffered severe and swift optic atrophy

BMPs are part of the TGF superfamily, which can regulate the cellular activities of B, NK, and myeloid cells (113)

The proposed mechanism involves maintaining synaptic vesicle integrity, competing for receptor sites, and potentially substituting for depleted neurotransmitters