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P53 activation causes downregulation of Nrf2 and generates higher levels of ROS, which promotes apoptosis ( 8.2 Exogenous Natural Inhibitors The complex tumor microenvironment limits the application of endogenous inhibitors

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Studies show that people with lung conditions like asthma and COPD tend to have lower levels of zinc and selenium than people who dont have these conditions ( Selenium and zinc deficiency may also increase the risk of respiratory infections, as well as the risk of severe symptoms and mortality in those with COVID-19 ( A study that analyzed data on 5,435 people found that a higher zinc intake was associated with a 42% reduced risk of developing lung cancer ( Making sure you get enough selenium and zinc from your diet is most important

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Patients with known liver disease were excluded