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Description

580 Alpha-lipoic acid exerts its neuroprotective effects by inhibiting calpain1 activity of and significantly reducing Ca 2+ levels in mouse brain tissue

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However, D4 also shows off-target effects blocking other connexin channels, including Cx26, Cx30 and Cx45 522,523

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This is very important because a 10-year delay in cataract formation would significantly reduce the incidence of cataract blindness and decrease the need for surgery by 50%

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Similarly, Halczuk et al

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Archived from the original on 15 May 2019

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PMID: 28806994

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