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Acute GVHD was scored according to the MAGIC criteria ( Next-generation sequencing experiments and data analysis Targeted sequencing A total of 13 genes involved in cyclophosphamide activation and detoxification (CYP3A4, CYP3A5, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19 , GSTA1, GSTM1, GSTP1, GSTT1, ALDH1A1 and ALDH3A1 ) were genotyped ( Supplementary Table 1 ) in the recipient samples

Springer Link , doi:10.1007/s00394-019-01919-4

However, the hypoxic infection microenvironment and limited ROS yield of conventional sonosensitizers can restrict efficacy 255

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