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Glutathione-S-transferase is highly inducible in animals and humans, and its expression is affected by dietary factors that include lipids (Girn et al

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The first anatomical region subjected to filtered toxicants, the PCT with epithelial cells with resorptive capacity, is the most vulnerable region of the kidney 19

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Radioimmunotherapy is another alternative in which the cytotoxic effect of radiation can be delivered to the HSCs reducing the toxicity to other organs by conjugating radioisotopes to specific antibodies (119)