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Studies in germ-free NOD,MyD88-deficientKO mice also highlight a protective interaction of commensal microbes with the immune system that reduces the incidence of diabetes (110)

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A similar mechanistic study on ultraviolet-damaged skin cells found that 5 uM of sulforaphane induced the expression of Nrf2 target genes including NQO1 at 1.5 times the normal rate, which led to a significant reduction of sunburn damage in the cells

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Awandare GA,Spadafora C, Moch JK, Dutta S, Haynes JD, Stoute JA