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The literature demonstrates that oxidative stress, regardless of its origin, is associated with ototoxicity (13)

Pocai A, Lam TK, Gutierrez-Juarez R, Obici S, Schwartz GJ, Bryan J et al

Salem, S

Lipid hydroperoxides, which are formed during the peroxidation of lipids containing unsaturated fatty acids, are reduced, not by the usual GSH peroxidase, but by a special enzyme designed specifically to handle peroxidized fatty acids in phospholipids