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Lowering inflammatory cytokines Studies in Nature and Diabetes show that GLP-1 reduces cytokines such as TNF-alpha, IL-6, and IL-1, which are major players in autoimmune diseases and arthritis

As with many research peptides, observed responses can vary depending on study conditions and experimental models

Defer protocol in cases of acute infections until resolved

There is no validated human dosage, and no studies confirm injection safety in humans

The 503A designation is critical

But critics fear the FDAs stamp of approval will simply legitimize the use of unproven substances whose dangers may only become apparent in coming years