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Senescent cells are linked to many age-related conditions, including arthritis, poor wound healing, and neurodegenerative diseases like Alzheimers or Parkinsons, says senior and co-corresponding author Pam Maher, PhD, a research professor at Salk

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Cellular and molecular mechanisms of fibrosis

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The induction of MT expression is induced through metal regulatory transcription factor 1 (MTF-1), a 753 amino acid transcription factor, which directly responds to increased levels of free zinc(II) [62]