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Schmid C, Bianda T, Zwimpfer C, Zapf J, Wiesli P

and consider CBT

A cross-sectional study of 700 community-living, physically disabled women over the age of 65 found that vitamin B 12 -deficient women were twice as likely to be severely depressed as non-deficient women (97)

I've since bought up-to-date ampoules and, having various symptoms which may be related to low levels, I've decided to do alt days for a couple of weeks, then back to 2-3 monthly

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In two similar, randomized, placebo-controlled trials performed by one research group, six months of treatment with 2 mg folic acid, 25 mg B6, and 400 mcg B12 per day reduced the frequency of migraines better than placebo in women with migraines with aura, but 1 mg folic acid plus the same doses of B6 and B12 did not (Menon 2012