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Single nucleotide polymorphisms (SNPs) in receptors, enzymes, and transcription factors are also known to cause loss or gain of functions (491495)

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The study notes that the amount of decrease in Lp(a) is similar to that of using niacin or a PCSK9 inhibitor.[ref] Coconut oil instead of omega-6 oils: An intervention study looking at fat in the diet found that a diet high in saturated fat from coconut oil decreased Lp(a) by 17 mg/L, while a diet high in polyunsaturated fatty acids increased Lp(a) by 25 mg/L.[ref] High phenol olive oil: A small clinical trial showed that high phenol olive oil or large quantities of low phenol olive oil lowered Lp(a) levels a bit.[ref] Lowering cholesterol: Overall, lowering your LDL cholesterol numbers can help lower Lp(a) since Lp(a) is the carrier for LDL

Y.et al (2009)

Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity