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These preclinical findings support plausibility but require clinical corroboration per indication

Interleukin-1, interleukin-18, and the interleukin-1 converting enzyme

The control diet containing 2 mg FA/kg chow (normal replete) provides the experimentally determined folate daily requirement (DR) for laboratory rodents 38 endorsed by the American Institute of Nutrition for rodents 39 , corresponding to the human recommended dietary allowance of 400 g/d