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2) Alcohol GGT levels are elevated following prolonged alcohol use

Ito T, Inden M, Ueda T, Asaka Y, Kurita H, Hozumi I (2020) The neuroprotective effects of activated 7 nicotinic acetylcholine receptor against mutant copperzinc superoxide dismutase 1-mediated toxicity

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In our study, we found that the increased A plaques firstly appeared in the cortex and hippocampus of earlier 8-week ethanol exposed APP/PS1 mice (in both 2BC and IP paradigms), and no A plaque was found even after 10 weeks ethanol exposure in WT mice, suggesting that chronic ethanol exposure did not directly result in A plaques but accelerate the A deposition

Hahn, M.P

Kadioglu A, Kucukdurmaz F, Sanli O