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How to Use: Typical dosage is to inject 1 mL into the muscle or under the skin once per month Use a clean needle and syringe for each injection Follow your healthcare providers directions closely Warnings: Not for individuals with hypersensitivity to cobalt or vitamin B12 Use with caution in patients with Lebers disease or other optic nerve disorders In rare cases, high doses may lead to low potassium levels or allergic reactions

The GLP-1 fatigue guide and the GLP-1 headache guide provide broader context for these side effects across the entire class of incretin-based therapies, not just tirzepatide specifically

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Symptoms may include rash, itching, or swelling

10.3892/br.2018.1130 Biomed Rep