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(Source 1) Risk factors for vitamin B12 deficiency include: Pernicious anemia History of gastrointestinal or bariatric surgery Use of medications such as proton pump inhibitors and metformin Vegetarians and diets low in dairy products, animal protein, and fortified cereals (Source 1) Malabsorption issues (Source 1) The best treatment for vitamin B12 deficiency is supplementation

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Phototherapy and exchange transfusion may not be available in developing nations where G6PD deficiency is most common