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chap 83

FDA Finalizes Guidance on Patient-Focused Drug Development (PFDD) The new PFDD guidance reinforces that clinical trials must capture what matters most to patients symptom burden, quality of life, daily functioning, and treatment tolerability

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VDACs, located at the interface between the cytoplasm and mitochondria, function as transmembrane channels for the transport of ions and metabolites, helping to maintain energy homeostasis

This study also explored whether HT could prevent apoptosis through the inhibition of autophagic vacuoles, which is a cell-protective mechanism

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