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E., Smakhtin

Linus Pauling Institute Oregon State University Updated in January 2014 by: Barbara Delage, Ph.D

I posted a poll on Twitter that asked learners/users you would replace vitamin B 12 in a patient with pernicious anemia, focusing on the choice between intramuscular (IM) and oral (PO) routes

General precautions: Always take it under doctor's supervision Tell your doctor if you're pregnant or breastfeeding Don't skip doses randomly, consistency matters Store tablets away from heat and moisture Medical conditions to mention: Kidney disease Any ongoing allergy history Leber's disease (a rare eye condition, B12 can worsen it) Drug interactions: Some antibiotics and metformin can reduce B12 absorption Always share your full medicine list with your doctor When to Consult a Doctor

By carefully considering these factors and selecting the appropriate needle size for B12 injections, healthcare providers can promote effective, safe, and comfortable administration of the vitamin

Severe cramps, not responding to stretching or pain medications, or associated with severe dehydration from over-exertion or illness (severe vomiting and/or diarrhea), may need treatment with intravenous (I.V.) fluids and electrolytes