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10.1016/0006-8993(88)90697-x 56 FeighnerJ

Laboratory studies have found falcarinol to inhibit specific inflammatory pathways, and population studies consistently show that people who eat more carotenoid-rich vegetables have lower markers of systemic inflammation

In contrast, AMYRs have high affinity and potency in response to amylin peptides, but weak response to human CT (hCT) 7,8

Iron homeostasis is disrupted in failing myocardial tissue (Sawicki et al., 2023[369]) While certain investigations of explanted human hearts from patients undergoing cardiac transplantation have revealed diminished mitochondrial iron levels, others have revealed elevated levels of mitochondrial iron and total cellular heme iron in failing human hearts (Sawicki et al., 2015[370])

NLRP3 inflammasome activation is required for fibrosis development in NAFLD

Rahaman MM, Hossain R, Herrera-Bravo J, Islam MT, Atolani O, Adeyemi OS, et al