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HGF-MET Signaling Shifts M1 Macrophages Toward an M2-Like Phenotype Through PI3K-Mediated Induction of Arginase-1 Expression

The handful of these nutrient-sensing mechanisms thus far identified have had a profound impact on human health

Metabolic syndrome and CKD in a general Japanese population: the Hisayama Study

Shamsah AH, Cartmell SH, Richardson SM, et al

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found the diabetic DPP4 H/M mice, which could express human DPP4 in the nonciliated epithelial cells and alveolar type 2 cells, exhibited more severe clinical symptoms characterized by a prolonged period of weight loss and clinical disease with a delay in the initiation of inflammation in the lung and slower inflammatory resolution after infection with MERS-CoV [193]