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NNMT inhibition with 5-Amino-1MQ reduced white adipose tissue mass by ~35% in diet-induced obese mouse models without suppressing food intake, suggesting energy expenditure modulation

Comparing experimental data in mice with clinical trial data, they found that inhibiting IL-17A intestinal inflammation further worsens the disease [15]

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Hamsters were treated with isoflurane lightly, and then 200 l of PBS was injected into one nasal opening while turbid wash was collected from the other one without any blood contamination