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the clinical relevance of this finding in humans is unknown, and in UK and EU prescribing information this is noted as a precaution rather than a formal contraindication but individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN2) should discuss this with their doctor

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A large quantity (85~90%) of CD38 high NK cells are killed

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In laboratory studies, it is sometimes used alongside other metabolic or mitochondrial research agents, depending on experimental design

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