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EGT production was abolished in A

Joint Bone Spine (2018)

PMID: 15565145[PubMed Reference] Goldstein AL, Hannappel E, Kleinman HK

Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1

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Epidemiological data further support this connection: patients with inflammatory bowel disease exhibit a 28%30% increased risk of developing PD (Zhu et al., 2019), and Epstein-Barr virus infection has been linked to PD-like symptoms, highlighting the potential role of immune dysregulation in PD pathogenesis (Espay and Henderson, 2011)